The Olfactory System: Part III: Central Processing of Olfaction and Central Olfactory Dysfunction

T.P. Naidich and P.M. Som

View Article on Neurographics Website

Date of Activity Release: Aug. 1, 2018
Date of Activity Expiration: Aug. 1, 2021

Target Audience:
Intended for neuroradiologists and neuroradiology trainees with varying degrees of experience.

Learning Objective:
This review is intended to help the reader: 1) to become familiar with the olfactory structures of the brain, 2) to understand how the brain transforms the physicochemical signature of an odorant molecule and/or mixture into the unified perception of an “odor object” that is imbued with salience, valence, and memory associations, and 3) to become aware of the intriguing links among olfactory dysfunction, sleep disturbance, dementias, and psychoses.

Parts I and II of this review discussed the detection of odor molecules within the primary olfactory mucosa of the nose, the transfer of the odorant data to the olfactory bulb, and the initial processing of the olfactory data within the bulb. Part III now extends that discussion inward and addresses the central processing of olfactory data by the primary olfactory cortex and further processing by secondary olfactory cortices and related portions of the brain. It then addresses the intriguing links among olfactory dysfunction, sleep disturbance, dementias, and psychoses.

Commercial Support
No commercial support was received for this activity.

Credit Designation Statement

The American Society of Neuroradiology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The American Society of Neuroradiology designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Method of Physician Participation:
Each participant will review the corresponding Neurographics article located at Upon completion, each physician will complete and pass a post-test with a score of at least 80% to receive a CME certificate.

All individuals in control of content have disclosed the following relevant financial relationships. All of these relationships were treated as a conflict of interest, and have been resolved (C7 SCS 6.1-6.2, 6.5)

Authors have no relevant financial relationships.





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