Neurographics

Neuroradiologic Findings in Sickle Cell Disease Excluding Moyamoya

C. Zamora; M. Castillo

View Article on Neurographics Website

Date of Activity Release: Feb. 1, 2017
Date of Activity Expiration: Feb. 1, 2020

Target Audience:
Intended for neuroradiologists and neuroradiology trainees with varying degrees of experience.

Learning Objectives:
Recognize relevant imaging features associated with sickle cell disease complications in the head, neck, and spine, other than moyamoya.

Abstract
The imaging manifestations of sickle cell disease are diverse and typically result from hypoxia, arterial wall damage, hemolysis, and repeated vasoocclusion with resultant ischemia, inflammation, and sometimes superimposed infection. We retrospectively reviewed all sickle cell disease cases from our teaching files and identified those with complications other than moyamoya, which formed the basis of this review. We were able to identify the following complications: spinal cord and vertebral infarctions, skull infarctions, extramedullary hematopoiesis, intraventricular and cerebral microhemorrhages, intracranial aneurysms, posterior reversible encephalopathy syndrome, and extracranial carotid stenoses. We presented a review of the imaging findings related to these complications.

Commercial Support
No commercial support was received for this activity.

Credit Designation Statement

The American Society of Neuroradiology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The American Society of Neuroradiology designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Method of Physician Participation:
Each participant will review the corresponding Neurographics article located at www.neurographics.org. Upon completion, each physician will complete and pass a post-test with a score of at least 80% to receive a CME certificate.

Disclosures:
All individuals in control of content have disclosed the following relevant financial relationships. All of these relationships were treated as a conflict of interest, and have been resolved (C7 SCS 6.1-6.2, 6.5)

Authors:
Authors have no relevant financial relationships.

Planners:

Name

Role

Relationship/Interest

Barton Branstetter 

Editor in Chief

None, N/A

Adam Flanders

Deputy Editor

Royalties, Lippincott Williams and Wilkins

Robert Quencer 

Consulting Editor

None, N/A

Mark Mullins

Associate Editor

Non-remunerative position, AUR6

Meng Law

Associate Editor

Stockholder, Clinical Imaging

Michele Johnson

Associate Editor

Consultant, Boston Scientific, Inc.

Edward Escott

Associate Editor

Grant, Atherysys, Inc.; Royalties, Thieme Medical Publishers

Scott Faro

Associate Editor

None, N/A

Tina Young Poussaint

Associate Editor

None, N/A

Dheeraj Ghandi

Associate Editor

Grant, Arstasis, Axera Inc.; Consultant, Covidien, EV3

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