Multiple Sclerosis: Self Assessment Module (SAM) SAM

Peter A. Calabresi, MD; Daniel S. Reich, MD, PhD; Aaron S. Field, MD, PhD

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Target Audience:

The ASNR 54th Annual Meeting is the premier Neuroradiology meeting in the world. The target audience includes:

  • Neuroradiologists in practice and research
  • General radiologists who read Neuroradiology studies
  • Young professionals and trainees
  • Brain, Spine, and Head and Neck imaging Scientists
  • Clinicians from related disciplines

About This Module:

This module is composed of three parts:
  • MS Diagnosis and Therapy: State of the Science Peter A. Calabresi, MD
  • Advanced Neuroimaging in MS Daniel S. Reich, MD, PhD
  • Differential Diagnosis in MS Imaging Aaron S. Field, MD, PhD


Upon completion of this module, participants should be able to:

Part I: MS Diagnosis and Therapy: State of the Science Peter A. Calabresi, MD

  1. Describe multiple sclerosis pathogenesis
  2. Apply McDonald diagnostic criteria and specify the utility of MRI
  3. List MS anti-inflammatory therapies and explain the role of MRI in prognosis and assessment of efficacy

Part II: Advanced Neuroimaging in MS Daniel S. Reich, MD, PhD

  1. Outline the proposed new MRI diagnostic criteria for MS
  2. Recognize group-level imaging markers
  3. Describe new and emerging individual-level imaging approaches

Part III: Differential Diagnosis in MS Imaging Aaron S. Field, MD, PhD

  1. List the most common causes of misdiagnosis in MS and its imaging mimics, and the role of the radiologist in avoiding misdiagnosis.
  2. Describe the imaging features that favor a diagnosis of MS as well as those that suggest an alternative diagnosis.

Commercial Support

No commercial support was received for this activity.

Accreditation Statement

The American Society of Neuroradiology (ASNR) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit Designation Statement

ASNR designates this enduring material for a maximum of AMA PRA Category 1 Credits. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Method of Physician Participation:

Each physician will listen to each audio self-directed module while following along with the visual slides. Upon completion, each physician will answer evaluation questions and pass a post test with at least a score of 80% to receive their CME certificate.

Disclosures: All individuals in control of content have disclosed the following relevant financial relationships. All of these relationships were treated as a conflict of interest, and have been resolved (C7 SCS 6.1-6.2, 6.5)


  • Howard A. Rowley, MD, 2016 Program Chair/President-Elect, has no relevant financial relationships.
  • C. Douglas Phillips, MD, FACR, Chair, Web and Online Education Subcommittee of ASNR Education Committee, has no relevant financial relationships.
  • Angelo Artemakis, ASNR staff, has no relevant financial relationships.


  • Peter A. Calabresi, MD:
    • Dr. Calabresi has received consulting fees from Vertex
    • Dr. Calabresi is PI on grants to Johns Hopkins from Biogen, MedImmune and Vertex
  • Daniel S. Reich, MD, PhD:
    • Almost all of my work is funded by NINDS.
    • Trainees in my lab have received support from the National MS Society, the American Brain Foundation, and the Foundation of the Consortium of MS Centers.
    • We have Cooperative Research and Development Agreements with the Myelin Repair Foundation and Vertex Pharmaceuticals
  • Aaron S. Field, MD, PhD, has no relevant financial relationships.

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