Imaging of Cerebral Radionecrosis: Collateral Damage from Head and Neck Radiation Inferior Petrosal Venous Sinus Sampling Inferior Petrosal Venous Sinus Sampling

Landry, D.; Garsa, A.A.; Glastonbury, C.M.

View Article on Neurographics Website

Date of Activity Release: June 1, 2016
Date of Activity Expiration: June 1, 2019

Target Audience:
Intended for neuroradiologists and neuroradiology trainees with varying degrees of experience.

Learning Objectives:
Recognize typical imaging patterns as well as advanced imaging features of radiation-induced brain injury after radiation therapy for head and neck malignancies.

Head and neck malignancies are often treated by external beam radiation therapy, either alone or in combination with surgery and/or chemotherapy. Because of the proximity of head and neck malignancies to brain parenchyma, it is often impossible to exclude neuronal tissue from the radiation field. Because neuronal tissue is sensitive to high-dose radiation, brain injury may be evident on posttreatment imaging studies. The goal of this article was to present the typical appearance and the pitfalls of brain injury that occur with external beam radiation therapy for head and neck malignancies. The contribution of advanced imaging modalities, such as susceptibility-weighted imaging, MR perfusion, and MR spectroscopy, are discussed.

Commercial Support
No commercial support was received for this activity.

Credit Designation Statement

The American Society of Neuroradiology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The American Society of Neuroradiology designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Method of Physician Participation:
Each participant will review the corresponding Neurographics article located at Upon completion, each physician will complete and pass a post-test with a score of at least 80% to receive a CME certificate.

All individuals in control of content have disclosed the following relevant financial relationships. All of these relationships were treated as a conflict of interest, and have been resolved (C7 SCS 6.1-6.2, 6.5)

Authors have no relevant financial relationships.





Barton Branstetter 

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Stockholder, Clinical Imaging

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Grant, Atherysys, Inc.; Royalties, Thieme Medical Publishers

Scott Faro

Associate Editor

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Tina Young Poussaint

Associate Editor

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Dheeraj Ghandi

Associate Editor

Grant, Arstasis, Axera Inc.; Consultant, Covidien, EV3

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